C | SK | CHEMISTRY; METALLURGY |
C12 | KL | BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING |
C12N | UKL | MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF (biocides, pest repellants or attractants, or plant growth regulators containing micro-organisms, viruses, microbial fungi, enzymes, fermentates, or substances produced by, or extracted from, micro-organisms or animal material A01N 63/00; food compositions A21 , A23; medicinal preparations A61K; chemical aspects of, or use of materials for, bandages, dressings, absorbent pads or surgical articles A61L; fertilisers C05); PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS (preservation of living parts of humans or animals A01N 1/02); MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA (microbiological testing media C12Q) [3] |
C12N 1/00 | HGR | Micro-organisms, e.g. protozoa; Compositions thereof (medicinal preparations containing material from micro-organisms A61K 35/66; preparing medicinal bacterial antigen or antibody compositions, e.g. bacterial vaccines, A61K 39/00); Processes of propagating, maintaining or preserving micro-organisms or compositions thereof; Processes of preparing or isolating a composition containing a micro-organism; Culture media therefor [3] |
C12N 1/02 | UGR1 | . | Separating micro-organisms from their culture media [3] |
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C12N 1/04 | UGR1 | . | Preserving or maintaining viable micro-organisms (immobilised micro-organisms C12N 11/00) [3] |
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C12N 1/06 | UGR1 | . | Lysis of micro-organisms [3] |
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C12N 1/08 | UGR1 | . | Reducing the nucleic acid content [3] |
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C12N 1/10 | UGR1 | . | Protozoa; Culture media therefor [3] |
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C12N 1/11 | UGR2 | . . | modified by introduction of foreign genetic material [5] |
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C12N 1/12 | UGR1 | . | Unicellular algae; Culture media therefor (culture of multi-cellular plants A01G; as new plants A01H 13/00) [3] |
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C12N 1/13 | UGR2 | . . | modified by introduction of foreign genetic material [5] |
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C12N 1/14 | UGR1 | |
C12N 1/15 | UGR2 | . . | modified by introduction of foreign genetic material [5] |
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C12N 1/16 | UGR2 | . . | Yeasts; Culture media therefor [3] |
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C12N 1/18 | UGR3 | . . . | Baker's yeast; Brewer's yeast [3] |
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C12N 1/19 | UGR3 | . . . | modified by introduction of foreign genetic material [5] |
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C12N 1/20 | UGR1 | . | Bacteria; Culture media therefor [3] |
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C12N 1/21 | UGR2 | . . | modified by introduction of foreign genetic material [5] |
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C12N 1/22 | UGR1 | . | Processes using, or culture media containing, cellulose or hydrolysates thereof [3] |
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C12N 1/24 | UGR1 | . | Processes using, or culture media containing, waste sulfite liquor [3] |
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C12N 1/26 | UGR1 | . | Processes using, or culture media containing, hydrocarbons (refining of hydrocarbon oils by using micro-organisms C10G 32/00) [3] |
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C12N 1/28 | UGR2 | |
C12N 1/30 | UGR3 | . . . | having five or less carbon atoms [3] |
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C12N 1/32 | UGR1 | . | Processes using, or culture media containing, lower alkanols, i.e. C_1_ to C_6_ [3] |
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C12N 1/34 | UGR1 | . | Processes using foam culture [3] |
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C12N 1/36 | UGR1 | . | Adaptation or attenuation of cells [3] |
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C12N 1/38 | UGR1 | . | Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound (C12N 1/34 takes precedence) [3] |
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C12N 3/00 | HGR | Spore-forming or isolating processes [3] |
C12N 5/00 | HGR | Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor (plant reproduction by tissue culture techniques A01H 4/00) [3, 5] |
C12N 5/02 | UGR1 | . | Propagation of single cells or cells in suspension; Maintenance thereof; Culture media therefor [3] |
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C12N 5/04 | UGR1 | . | Plant cells or tissues [5] |
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C12N 5/06 | UGR1 | . | Animal cells or tissues [5] |
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C12N 5/08 | UGR1 | . | Human cells or tissues [5] |
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C12N 5/10 | UGR1 | . | Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells [5] |
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C12N 5/12 | UGR2 | . . | Fused cells, e.g. hybridomas [5] |
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C12N 5/14 | UGR3 | |
C12N 5/16 | UGR3 | |
C12N 5/18 | UGR4 | . . . . | Murine cells, e.g. mouse cells [5] |
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C12N 5/20 | UGR5 | . . . . . | one of the fusion partners being a B lymphocyte [5] |
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C12N 5/22 | UGR3 | |
C12N 5/24 | UGR4 | . . . . | one of the fusion partners being a B lymphocyte [5] |
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C12N 5/26 | UGR3 | . . . | Cells resulting from interspecies fusion [5] |
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C12N 5/28 | UGR4 | . . . . | one of the fusion partners being a human cell [5] |
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C12N 7/00 | HGR | Viruses, e.g. bacteriophages; Compositions thereof; Preparation or purification thereof (medicinal preparations containing viruses A61K 35/76; preparing medicinal viral antigen or antibody compositions, e.g. virus vaccines, A61K 39/00) [3] |
C12N 7/01 | UGR1 | . | Viruses, e.g. bacteriophages, modified by introduction of foreign genetic material (vectors C12N 15/00) [5] |
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C12N 7/02 | UGR1 | . | Recovery or purification [3] |
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C12N 7/04 | UGR1 | . | Inactivation or attenuation; Producing viral sub-units [3] |
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C12N 7/06 | UGR2 | . . | by chemical treatment [3] |
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C12N 7/08 | UGR2 | . . | by serial passage of virus [3] |
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C12N 9/00 | HGR | Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof (preparations containing enzymes for cleaning teeth A61K 7/28; medicinal preparations containing enzymes or proenzymes A61K 38/43; enzyme containing detergent compositions C11D); Processes for preparing, activating, inhibiting, separating, or purifying enzymes (preparation of malt C12C 1/00) [3] |
C12N 9/02 | UGR1 | . | Oxidoreductases (1.), e.g. luciferase [3] |
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C12N 9/04 | UGR2 | . . | acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1) [3] |
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C12N 9/06 | UGR2 | . . | acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7) [3] |
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C12N 9/08 | UGR2 | . . | acting on hydrogen peroxide as acceptor (1.11) [3] |
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C12N 9/10 | UGR1 | . | Transferases (2.) (ribonucleases C12N 9/22) [3] |
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C12N 9/12 | UGR2 | . . | transferring phosphorus containing groups, e.g. kinases (2.7) [3] |
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C12N 9/14 | UGR1 | |
C12N 9/16 | UGR2 | . . | acting on ester bonds (3.1) [3] |
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C12N 9/18 | UGR3 | . . . | Carboxylic ester hydrolases [3] |
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C12N 9/20 | UGR4 | . . . . | Triglyceride splitting, e.g. by means of lipase [3] |
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C12N 9/22 | UGR3 | |
C12N 9/24 | UGR2 | . . | acting on glycosyl compounds (3.2) [3] |
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C12N 9/26 | UGR3 | . . . | acting on alpha-1, 4-glucosidic bonds, e.g. hyaluronidase, invertase, amylase [3] |
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C12N 9/28 | UGR4 | . . . . | Alpha-amylase from microbial source, e.g. bacterial amylase [3] |
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C12N 9/30 | UGR5 | . . . . . | Fungal source [3] |
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C12N 9/32 | UGR4 | . . . . | Alpha-amylase from plant source [3] |
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C12N 9/34 | UGR4 | |
C12N 9/36 | UGR3 | . . . | acting on beta-1, 4 bonds between N-acetylmuramic acid and 2-acetylamino 2-deoxy-D-glucose, e.g. lysozyme [3] |
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C12N 9/38 | UGR3 | . . . | acting on beta-galactose-glycoside bonds, e.g. beta-galactosidase [3] |
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C12N 9/40 | UGR3 | . . . | acting on alpha-galactose-glycoside bonds, e.g. alpha-galactosidase [3] |
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C12N 9/42 | UGR3 | . . . | acting on beta-1, 4-glucosidic bonds, e.g. cellulase [3] |
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C12N 9/44 | UGR3 | . . . | acting on alpha-1, 6-glucosidic bonds, e.g. isoamylase, pullulanase [3] |
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C12N 9/46 | UGR4 | |
C12N 9/48 | UGR2 | . . | acting on peptide bonds, e.g. thromboplastin, leucine aminopeptidase (3.4) [3] |
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C12N 9/50 | UGR3 | |
C12N 9/52 | UGR4 | . . . . | derived from bacteria [3] |
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C12N 9/54 | UGR5 | . . . . . | bacteria being Bacillus [3] |
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C12N 9/56 | UGR6 | . . . . . . | Bacillus subtilis or Bacillus licheniformis [3] |
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C12N 9/58 | UGR4 | . . . . | derived from fungi [3] |
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C12N 9/60 | UGR5 | |
C12N 9/62 | UGR5 | . . . . . | from Aspergillus [3] |
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C12N 9/64 | UGR4 | . . . . | derived from animal tissue, e.g. rennin [3] |
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C12N 9/66 | UGR3 | |
C12N 9/68 | UGR3 | . . . | Plasmin, i.e. fibrinolysin [3] |
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C12N 9/70 | UGR3 | |
C12N 9/72 | UGR3 | |
C12N 9/74 | UGR3 | |
C12N 9/76 | UGR3 | . . . | Trypsin; Chymotrypsin [3] |
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C12N 9/78 | UGR2 | . . | acting on carbon to nitrogen bonds other than peptide bonds (3.5) [3] |
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C12N 9/80 | UGR3 | . . . | acting on amide bonds in linear amides [3] |
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C12N 9/82 | UGR4 | |
C12N 9/84 | UGR4 | . . . . | Penicillin amidase [3] |
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C12N 9/86 | UGR3 | . . . | acting on amide bonds in cyclic amides, e.g. penicillinase [3] |
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C12N 9/88 | UGR1 | |
C12N 9/90 | UGR1 | |
C12N 9/92 | UGR2 | |
C12N 9/94 | UGR1 | |
C12N 9/96 | UGR1 | . | Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates [3] |
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C12N 9/98 | UGR1 | . | Preparation of granular or free-flowing enzyme compositions (C12N 9/96 takes precedence) [3] |
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C12N 9/99 | UGR1 | . | Enzyme inactivation by chemical treatment [3] |
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C12N 11/00 | HGR | Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof [3] |
C12N 11/02 | UGR1 | . | Enzymes or microbial cells being immobilised on or in an organic carrier [3] |
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C12N 11/04 | UGR2 | . . | entrapped within the carrier, e.g. gel, hollow fibre [3] |
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C12N 11/06 | UGR2 | . . | attached to the carrier via a bridging agent [3] |
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C12N 11/08 | UGR2 | . . | the carrier being a synthetic polymer [3] |
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C12N 11/10 | UGR2 | . . | the carrier being a carbohydrate [3] |
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C12N 11/12 | UGR3 | . . . | Cellulose or derivatives thereof [3] |
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C12N 11/14 | UGR1 | . | Enzymes or microbial cells being immobilised on or in an inorganic carrier [3] |
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C12N 11/16 | UGR1 | . | Enzymes or microbial cells being immobilised on or in a biological cell [3] |
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C12N 11/18 | UGR1 | . | Multi-enzyme systems [3] |
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C12N 13/00 | HGR | Treatment of micro-organisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves [3] |
C12N 15/00 | HGR | Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (mutants or genetically engineered micro-organisms C12N 1/00 , C12N 5/00 , C12N 7/00; new plants A01H; plant reproduction by tissue culture techniques A01H 4/00; new animals A01K 67/00; use of medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases, gene therapy A61K 48/00; peptides in general C07K) [3, 5, 6] |
C12N 15/01 | UGR1 | . | Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor [5] |
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C12N 15/02 | UGR1 | . | Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion [5] |
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C12N 15/03 | UGR2 | |
C12N 15/04 | UGR2 | |
C12N 15/05 | UGR2 | |
C12N 15/06 | UGR2 | |
C12N 15/07 | UGR2 | |
C12N 15/08 | UGR2 | . . | Cells resulting from interspecies fusion [5] |
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C12N 15/09 | UGR1 | . | Recombinant DNA-technology [5] |
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C12N 15/10 | UGR2 | . . | Processes for the isolation, preparation or purification of DNA or RNA (chemical preparation of DNA or RNA C07H 21/00; preparation of non-structural polynucleotides from micro-organisms or with enzymes C12P 19/34) [5] |
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C12N 15/11 | UGR2 | . . | DNA or RNA fragments; Modified forms thereof (DNA or RNA not used in recombinant technology C07H 21/00) [5] |
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C12N 15/12 | UGR3 | . . . | Genes encoding animal proteins [5] |
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C12N 15/13 | UGR4 | . . . . | Immunoglobulins [5] |
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C12N 15/14 | UGR4 | . . . . | Human serum albumins [5] |
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C12N 15/15 | UGR4 | . . . . | Protease inhibitors, e.g. antithrombin, antitrypsin, hirudin [5] |
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C12N 15/16 | UGR4 | |
C12N 15/17 | UGR5 | |
C12N 15/18 | UGR5 | . . . . . | Growth hormones [5] |
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C12N 15/19 | UGR4 | . . . . | Interferons; Lymphokines; Cytokines [5] |
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C12N 15/20 | UGR5 | |
C12N 15/21 | UGR6 | . . . . . . | Alpha-interferons [5] |
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C12N 15/22 | UGR6 | . . . . . . | Beta-interferons [5] |
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C12N 15/23 | UGR6 | . . . . . . | Gamma-interferons [5] |
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C12N 15/24 | UGR5 | . . . . . | Interleukins [5] |
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C12N 15/25 | UGR6 | . . . . . . | Interleukin-1 [5] |
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C12N 15/26 | UGR6 | . . . . . . | Interleukin-2 [5] |
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C12N 15/27 | UGR5 | . . . . . | Colony stimulating factors [5] |
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C12N 15/28 | UGR5 | . . . . . | Tumor necrosis factors [5] |
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C12N 15/29 | UGR3 | . . . | Genes encoding plant proteins, e.g. thaumatin [5] |
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C12N 15/30 | UGR3 | . . . | Genes encoding protozoal proteins, e.g. from Plasmodium, Trypanosoma, Eimeria [5] |
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C12N 15/31 | UGR3 | . . . | Genes encoding microbial proteins, e.g. enterotoxins [5] |
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C12N 15/32 | UGR4 | . . . . | Bacillus crystal proteins [5] |
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C12N 15/33 | UGR4 | . . . . | Genes encoding viral proteins [5] |
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C12N 15/34 | UGR5 | . . . . . | Proteins from DNA viruses [5] |
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C12N 15/35 | UGR6 | . . . . . . | Parvoviridae, e.g. feline panleukopenia virus, human parvovirus [5] |
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C12N 15/36 | UGR6 | . . . . . . | Hepadnaviridae [5] |
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C12N 15/37 | UGR6 | . . . . . . | Papovaviridae, e.g. papillomaviruses, polyomavirus, SV40 [5] |
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C12N 15/38 | UGR6 | . . . . . . | Herpetoviridae, e.g. herpes simplex virus, varicella-zoster virus, Epstein-Barr virus, cytomegalovirus, pseudorabies virus [5] |
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C12N 15/39 | UGR6 | . . . . . . | Poxviridae, e.g. vaccinia virus, variola virus [5] |
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C12N 15/40 | UGR5 | . . . . . | Proteins from RNA viruses, e.g. flaviviruses [5] |
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C12N 15/41 | UGR6 | . . . . . . | Picornaviridae, e.g. rhinovirus, coxsackie viruses, echoviruses, enteroviruses [5] |
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C12N 15/42 | UGR7 | . . . . . . . | Foot-and-mouth disease virus [5] |
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C12N 15/43 | UGR7 | . . . . . . . | Poliovirus [5] |
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C12N 15/44 | UGR6 | . . . . . . | Orthomyxoviridae, e.g. influenza virus [5] |
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C12N 15/45 | UGR6 | . . . . . . | Paramyxoviridae, e.g. measles virus, mumps virus, Newcastle disease virus, canine distemper virus, rinderpest virus, respiratory syncytial viruses [5] |
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C12N 15/46 | UGR6 | . . . . . . | Reoviridae, e.g. rotavirus, bluetongue virus, Colorado tick fever virus [5] |
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C12N 15/47 | UGR6 | . . . . . . | Rhabdoviridae, e.g. rabies viruses, vesicular stomatitis virus [5] |
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C12N 15/48 | UGR6 | . . . . . . | Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, HIV [5] |
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C12N 15/49 | UGR7 | . . . . . . . | Lentiviridae, e.g. immunodeficiency viruses, visna-maedi virus, equine infectious anaemia virus [5] |
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C12N 15/50 | UGR6 | . . . . . . | Coronaviridae, e.g. infectious bronchitis virus, transmissible gastroenteritis virus [5] |
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C12N 15/51 | UGR5 | . . . . . | Hepatitis viruses [5] |
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C12N 15/52 | UGR3 | . . . | Genes encoding for enzymes or proenzymes [5] |
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C12N 15/53 | UGR4 | . . . . | Oxidoreductases (1) [5] |
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C12N 15/54 | UGR4 | . . . . | Transferases (2) [5] |
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C12N 15/55 | UGR4 | . . . . | Hydrolases (3) [5] |
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C12N 15/56 | UGR5 | . . . . . | acting on glycosyl compounds (3.2), e.g. amylase, galactosidase, lysozyme [5] |
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C12N 15/57 | UGR5 | . . . . . | acting on peptide bonds (3.4) [5] |
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C12N 15/58 | UGR6 | . . . . . . | Plasminogen activators, e.g. urokinase, TPA [5] |
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C12N 15/59 | UGR6 | |
C12N 15/60 | UGR4 | |
C12N 15/61 | UGR4 | . . . . | Isomerases (5) [5] |
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C12N 15/62 | UGR3 | . . . | DNA sequences coding for fusion proteins [5] |
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C12N 15/63 | UGR2 | . . | Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression [5] |
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C12N 15/64 | UGR3 | . . . | General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host [5] |
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C12N 15/65 | UGR3 | . . . | using markers (enzymes used as markers C12N 15/52) [5] |
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C12N 15/66 | UGR3 | . . . | General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease [5] |
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C12N 15/67 | UGR3 | . . . | General methods for enhancing the expression [5] |
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C12N 15/68 | UGR4 | . . . . | Stabilisation of the vector [5] |
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C12N 15/69 | UGR4 | . . . . | Increasing the copy number of the vector [5] |
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C12N 15/70 | UGR3 | . . . | Vectors or expression systems specially adapted for E. coli [5] |
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C12N 15/71 | UGR4 | . . . . | Expression systems using regulatory sequences derived from the trp-operon [5] |
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C12N 15/72 | UGR4 | . . . . | Expression systems using regulatory sequences derived from the lac-operon [5] |
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C12N 15/73 | UGR4 | . . . . | Expression systems using phage lambda regulatory sequences [5] |
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C12N 15/74 | UGR3 | . . . | Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora [5] |
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C12N 15/75 | UGR4 | |
C12N 15/76 | UGR4 | . . . . | for Actinomyces; for Streptomyces [5] |
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C12N 15/77 | UGR4 | . . . . | for Corynebacterium; for Brevibacterium [5] |
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C12N 15/78 | UGR4 | . . . . | for Pseudomonas [5] |
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C12N 15/79 | UGR3 | . . . | Vectors or expression systems specially adapted for eukaryotic hosts; [5] |
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C12N 15/80 | UGR4 | |
C12N 15/81 | UGR5 | |
C12N 15/82 | UGR4 | . . . . | for plant cells [5] |
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C12N 15/83 | UGR5 | . . . . . | Viral vectors, e.g. cauliflower mosaic virus [5] |
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C12N 15/84 | UGR5 | |
C12N 15/85 | UGR4 | . . . . | for animal cells [5] |
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C12N 15/86 | UGR5 | . . . . . | Viral vectors [5] |
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C12N 15/861 | UGR6 | . . . . . . | Adenoviral vectors [7] |
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C12N 15/863 | UGR6 | . . . . . . | Poxviral vectors, e.g. vaccinia virus [7] |
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C12N 15/864 | UGR6 | . . . . . . | Parvoviral vectors [7] |
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C12N 15/866 | UGR6 | . . . . . . | Baculoviral vectors [7] |
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C12N 15/867 | UGR6 | . . . . . . | Retroviral vectors [7] |
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C12N 15/869 | UGR6 | . . . . . . | Herpesviral vectors [7] |
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C12N 15/87 | UGR2 | . . | Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation [5] |
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C12N 15/88 | UGR3 | . . . | using micro-encapsulation, e.g. using liposome vesicle [5] |
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C12N 15/89 | UGR3 | . . . | using micro-injection [5] |
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C12N 15/90 | UGR3 | . . . | Stable introduction of foreign DNA into chromosome [5] |
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