Bibliografische Daten

Dokument US000007485742B2 (Seiten: 27)

Bibliografische Daten Dokument US000007485742B2 (Seiten: 27)
INID Kriterium Feld Inhalt
54 Titel TI [EN] Non-glycosidic and non-peptidic inhibitors of selectin, and the use thereof
71/73 Anmelder/Inhaber PA UNIV MAINZ JOHANNES GUTENBERG, DE
72 Erfinder IN DANNHARDT GERD, DE ; LUXENBURGER ANDREAS, DE ; PRECH PHILIP, DE ; ULBRICH HOLGER, DE
22/96 Anmeldedatum AD 26.07.2005
21 Anmeldenummer AN 57221405
Anmeldeland AC US
Veröffentlichungsdatum PUB 03.02.2009
33
31
32
Priorität PRC
PRN
PRD
DE
102004036213
20040726
33
31
32
PRC
PRN
PRD
EP
2005008125
20050726
51 IPC-Hauptklasse ICM C07C 205/00 (2006.01)
51 IPC-Nebenklasse ICS C07C 229/00 (2006.01)
C07C 249/00 (2006.01)
IPC-Zusatzklasse ICA
IPC-Indexklasse ICI
Gemeinsame Patentklassifikation CPC Neues Fenster: Externer Link Gemeinsame Patentklassifikation C07C 235/24 C07C 235/24
Neues Fenster: Externer Link Gemeinsame Patentklassifikation A61P 29/00 A61P 29/00
Neues Fenster: Externer Link Gemeinsame Patentklassifikation C07C 251/54 C07C 251/54
Neues Fenster: Externer Link Gemeinsame Patentklassifikation A61P 43/00 A61P 43/00
MCD-Hauptklasse MCM C07C 205/00 (2006.01)
MCD-Nebenklasse MCS C07C 229/00 (2006.01)
C07C 249/00 (2006.01)
MCD-Zusatzklasse MCA
57 Zusammenfassung AB [EN] A new class of non-glycosidic and non-peptidic inhibitors of selectins with low molecular weight according to the general formula 1 is described, as well as methods for their production. These compounds represent a new class of non-toxic, in vivo anti-inflammatory effective inhibitors of selectins, and do not exhibit the disadvantages of the glycosidic inhibitor complexes, and are furthermore more potent in vitro, compared to the known drug bimosiamose. Furthermore, medicaments containing the compounds and their uses in the treatment of diseases are described.
Korrekturinformation KORRINF
56 Entgegengehaltene Patentdokumente/Zitate,
in Recherche ermittelt
CT
56 Entgegengehaltene Patentdokumente/Zitate,
vom Anmelder genannt
CT
EP000000671407A2
JP000H11140038A
56 Entgegengehaltene Nichtpatentliteratur/Zitate,
in Recherche ermittelt
CTNP Helvetica Chimica Acta (1987), 70(1), 153-7. 0
56 Entgegengehaltene Nichtpatentliteratur/Zitate,
vom Anmelder genannt
CTNP Ulbrich, Holger, Einar E. Eriksson and Lennart Lindbom "Leukocyte and endothelial cell adhesion molecules as targets for therapeutic interventions in inflammatory disease" Trends in Pharmacological Sciences, Dec. 2003, vol. 24(12):640-647. 1;
Wong, Chi-Huey et al., "Small Molecules as Structural and Functional Mimics of Sialyl Lewis X Tetrasaccharide in Selectin Inhibition: A Remarkable Enhancement of Inhibition by Additional Negative Charge and/or Hydrophobic Group" J. Am. Chem. Soc., 1997, vol. 119:8152-8158. 1
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Sequenzprotokoll
Prüfstoff-IPC ICP C07C 205/00 ; C07C 229/00 ; C07C 249/00