Bibliografische Daten

Dokument US000006288104B1 (Seiten: 13)

Bibliografische Daten Dokument US000006288104B1 (Seiten: 13)
INID Kriterium Feld Inhalt
54 Titel TI [EN] Pharmaceutical compositions containing mesembrine and related compounds
71/73 Anmelder/Inhaber PA PHARMA NATURA PTY LTD, ZA
72 Erfinder IN GERICKE NIGEL PETER, ZA ; VAN WYK BEN-ERIK, ZA
22/96 Anmeldedatum AD 22.03.1999
21 Anmeldenummer AN 19483699
Anmeldeland AC US
Veröffentlichungsdatum PUB 11.09.2001
33
31
32
Priorität PRC
PRN
PRD
GB
9701493
19970603
33
31
32
PRC
PRN
PRD
ZA
964595
19960604
51 IPC-Hauptklasse ICM A61K 31/40
51 IPC-Nebenklasse ICS
IPC-Zusatzklasse ICA
IPC-Indexklasse ICI
Gemeinsame Patentklassifikation CPC Neues Fenster: Externer Link Gemeinsame Patentklassifikation A61K 31/404 A61K 31/404
Neues Fenster: Externer Link Gemeinsame Patentklassifikation A61P 3/04 A61P 3/04
Neues Fenster: Externer Link Gemeinsame Patentklassifikation C07D 209/32 C07D 209/32
Neues Fenster: Externer Link Gemeinsame Patentklassifikation C07D 209/08 C07D 209/08
Neues Fenster: Externer Link Gemeinsame Patentklassifikation A61P 25/32 A61P 25/32
Neues Fenster: Externer Link Gemeinsame Patentklassifikation A61P 43/00 A61P 43/00
Neues Fenster: Externer Link Gemeinsame Patentklassifikation A61P 25/04 A61P 25/04
Neues Fenster: Externer Link Gemeinsame Patentklassifikation A61P 25/22 A61P 25/22
Neues Fenster: Externer Link Gemeinsame Patentklassifikation A61P 25/20 A61P 25/20
Neues Fenster: Externer Link Gemeinsame Patentklassifikation A61P 25/24 A61P 25/24
Neues Fenster: Externer Link Gemeinsame Patentklassifikation A61P 3/00 A61P 3/00
MCD-Hauptklasse MCM C07D 209/12 (2006.01)
MCD-Nebenklasse MCS A61K (2006.01)
A61K 31/00 (2006.01)
A61K 31/40 (2006.01)
A61K 31/403 (2006.01)
A61K 31/404 (2006.01)
C07D 209/32 (2006.01)
A61P 3/04 (2006.01)
A61P 25/04 (2006.01)
A61P 43/00 (2006.01)
C07D (2006.01)
C07D 209/08 (2006.01)
A61P 3/00 (2006.01)
MCD-Zusatzklasse MCA
57 Zusammenfassung AB [EN] There is disclosed the use of mesembrine and related compounds (e.g. mesembranol, mesembranone) as scrotonin-uptake inhibitors, pharmaceutical compositions comprising such compounds or dry material or an extract of plants from the Mesembryanthemaceae family (e.g. Sceletium (Aizoaceae) tortuosum) containing a standardized content of said compounds, for use in the treatment of depressive states, psychological or psychiatric disorders with an anxiety component, alcohol and drug dependence, bulimia nervosa and obsessive-compulsive disorders. Also disclosed are new derivatives of mesembrine.
Korrekturinformation KORRINF
56 Entgegengehaltene Patentdokumente/Zitate,
in Recherche ermittelt
CT
56 Entgegengehaltene Patentdokumente/Zitate,
vom Anmelder genannt
CT JP000046043538A
JP000046043539A
DE000003604112A1
56 Entgegengehaltene Nichtpatentliteratur/Zitate,
in Recherche ermittelt
CTNP
56 Entgegengehaltene Nichtpatentliteratur/Zitate,
vom Anmelder genannt
CTNP Capps et al., "Sceletium Alkaloids, Part 7.1 Structure and Absolute Stereochemistry of (-)-Mesembrane and 3'-Methoxy-4'-O-methyljoubertiamine, Two Minor Bases from S. Namaquense L. Bolus: X-Ray Analysis of (-)-Mesembrane Hydrochloride Monohydrate," J. Chem. Soc. Perkins Trans. 8:1098-1104 (1977). 1;
Hoshino et al., "Synthesis of Sceletium and Amaryllidaceae Alkaloids, ()-Mesembrine and ()-Dihydromaritidine, ()Epidihydromaritidine, (-Elwesine, and ()-Epielwesine1)," Chem. Pharm. Bull. 35:2734-2743 (1987). 1;
Jeffs et al., "Sceletium Alkaloids. VI. Minor Alkaloids of S. namaquense and S. strictum," J. Org. Chem. 39:2703-2710 (1974). 1;
Jeffs et al., "Total Syntheses of ()-Joubertinamine, and ()-N-Demethylmesembrenone," J. Org. Chem. 48:3861-3863 (1983). 1;
Kruger et al., "Minor Alkaloids from Sceletium Strictum L. Bol. The Structure of N-Demethylmesembrenol and N-Demthylmesembranol," Journal of the South African Chemical Institute XXIV:235-237 (1971). 1;
Langlois et al., "Recherches Dans La Serie Des Aryl-3 Pyrrolidines-II, Syntheses de Produits Apparentes a la Mesembrine et a La Crinine," Tetrahedron 27:5641-5652 (1971). 1;
Pfaffli et al., "Demethylierungen am Mesembrine," Helvetica Chimica Acta 56:347-355 (1973). 1;
Smith et al., "Psychoactive constituents of the genus Sceletium N.E.Br. and otehr Mesembryanthemaceae: a review," Journal of Ethnopharmacology 50:119-130 (1996). 1;
Taguchi et al., "Synthesis of Octahydroindole Derivatives," Tetrahedrom Letters, 55:5763-5766 (1968). 1;
Taguchi et al., "Synthesis of Octhydroindole Derivatives," Chem. Pharm. Bull. 18:1008-1014 (1970). 1
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