| 54 |
Title |
TI |
[EN] ALBICIDIN DERIVATIVES, THEIR USE AND SYNTHESIS
[FR] DÉRIVÉS D'ALBICIDINE, LEUR UTILISATION ET LEUR SYNTHÈSE |
| 71/73 |
Applicant/owner |
PA |
CIRAD, FR
;
UNIV BERLIN TECH, DE
|
| 72 |
Inventor |
IN |
COCIANCICH STÉPHANE, FR
;
GRÄTZ STEFAN, DE
;
HÜGELLAND MANUELA, DE
;
KERWAT DENNIS, DE
;
KRETZ JULIAN, DE
;
PESIC ALEXANDER, DE
;
ROTT PHILLIPE, FR
;
ROYER MONIQUE, FR
;
SCHUBERT VIVIEN, DE
;
SÜSSMUTH RODERICH, DE
|
| 22/96 |
Application date |
AD |
Feb 14, 2014 |
| 21 |
Application number |
AN |
2014052922 |
|
Country of application |
AC |
EP |
|
Publication date |
PUB |
Aug 21, 2014 |
33
31
32 |
Priority data |
PRC
PRN
PRD |
EP
13170957
Jun 6, 2013
|
33
31
32 |
PRC
PRN
PRD |
EP
13192247
Nov 8, 2013
|
33
31
32 |
PRC
PRN
PRD |
EP
13199920
Dec 31, 2013
|
33
31
32 |
PRC
PRN
PRD |
EP
13199921
Dec 31, 2013
|
33
31
32 |
PRC
PRN
PRD |
EP
13199922
Dec 31, 2013
|
33
31
32 |
PRC
PRN
PRD |
US
201361765056
Feb 15, 2013
|
| 51 |
IPC main class |
ICM |
C07C 255/57
(2006.01)
|
| 51 |
IPC secondary class |
ICS |
A61K 31/277
(2006.01)
A61K 31/5375
(2006.01)
A61P 31/04
(2006.01)
C07C 233/83
(2006.01)
C07C 255/03
(2006.01)
C07C 311/21
(2006.01)
C07D 207/34
(2006.01)
C07D 241/28
(2006.01)
C07D 277/56
(2006.01)
C07D 295/14
(2006.01)
C07D 307/56
(2006.01)
C07D 317/08
(2006.01)
C07D 333/38
(2006.01)
C07F 9/09
(2006.01)
|
|
IPC additional class |
ICA |
|
|
IPC index class |
ICI |
|
|
Cooperative patent classification |
CPC |
A61P 31/04
A61P 31/06
C07C 233/83
C07C 237/42
C07C 255/03
C07C 255/29
C07C 255/44
C07C 255/57
C07C 2601/02
C07C 2601/08
C07C 2601/14
C07C 2601/18
C07C 2603/74
C07C 275/42
C07C 311/21
C07C 311/46
C07C 311/47
C07D 207/34
C07D 209/34
C07D 213/81
C07D 237/24
C07D 241/24
C07D 263/24
C07D 277/56
C07D 295/14
C07D 295/155
C07D 307/56
C07D 311/12
C07D 317/08
C07D 317/46
C07D 333/38
C07F 9/062
C07F 9/09
C07F 9/12
|
|
MCD main class |
MCM |
C07C 255/57
(2006.01)
|
|
MCD secondary class |
MCS |
A61K 31/277
(2006.01)
A61K 31/5375
(2006.01)
A61P 31/04
(2006.01)
C07C 233/83
(2006.01)
C07C 255/03
(2006.01)
C07C 311/21
(2006.01)
C07D 207/34
(2006.01)
C07D 241/28
(2006.01)
C07D 277/56
(2006.01)
C07D 295/14
(2006.01)
C07D 307/56
(2006.01)
C07D 317/08
(2006.01)
C07D 333/38
(2006.01)
C07F 9/09
(2006.01)
|
|
MCD additional class |
MCA |
|
| 57 |
Abstract |
AB |
[EN] The present invention relates to a antibiotically active compounds characterized by general formula (I), wherein X1, BB, BC, BD, BE and X2 are building blocks with D1, D2, D3, D4 or D5 being linkers which comprise carbon, sulphur, nitrogen, phosphor and/or oxygen atoms and which are covalently connecting the moities BA and BB, BB and BC, BC and BD, BD and BE and BE and BF, respectively, and wherein in particular the building block BC comprises an amino acid derivative. The invention relates further to said compounds for use in a method of treatment of diseases, in particular for use in a method of treatment of bacterial infections.
[FR] La présente invention concerne des composés actifs sur le plan antibiotique caractérisés par la formule générale (I), dans laquelle X1, BB, BC, BD, BE et X2 sont des synthons, D1, D2, D3, D4 ou D5 étant des lieurs qui comprennent des atomes de carbone, de soufre, d'azote, de phosphore et/ou d'oxygène et qui raccordent de manière covalente les fractions BA et BB, BB et BC, BC et BD, BD et BE et BE et BF, respectivement, et le synthon BC comprenant en particulier un dérivé d'acide aminé. L'invention concerne en outre lesdits composés pour leur utilisation dans un procédé de traitement de maladies, en particulier pour leur utilisation dans un procédé de traitement d'infections bactériennes. |
| 56 |
Cited documents identified in the search |
CT |
US000004525354A
US020110178104A1
WO002004035760A2
|
| 56 |
Cited documents indicated by the applicant |
CT |
|
| 56 |
Cited non-patent literature identified in the search |
CTNP |
DATABASE CAPLUS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; KAI, AKIYOSHI ET AL: "Preparation of benzamides as insecticides for agriculture and gardening", XP002727098, retrieved from STN Database accession no. 2006:1174191 7;
DATABASE CAPLUS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; LEI, GUANGDONG ET AL: "Method for preparing hydrogen bond-mediated self-assembly pyrazoline supramolecular polymer with blue fluorescent property", XP002727096, retrieved from STN Database accession no. 2010:482123 7;
DATABASE CAPLUS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; NAIR, ROSHNA V. ET AL: "A Synthetic Zipper Peptide Motif Orchestrated via Co-operative Interplay of Hydrogen Bonding, Aromatic Stacking, and Backbone Chirality", XP002727097, retrieved from STN Database accession no. 2013:1138927 7;
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 11 August 2011 (2011-08-11), XP002727101, retrieved from STN Database accession no. 1315923-72-8 7;
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 21 August 2011 (2011-08-21), XP002727102, retrieved from STN Database accession no. 1320744-17-9 7;
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 30 December 2008 (2008-12-30), XP002727100, retrieved from STN Database accession no. 1091978-94-7 7;
DATABASE REGISTRY [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; XP002727103, retrieved from STN Database accession no. 1319838-00-0 7;
LAURENCE DUTOT ET AL: "Synthesis and Characterisation of Helical beta-Peptide Srchitectures that Contain (s)-beata3-HDOPA(Crown Ether) Derivatives", CHEM. EUR. J., vol. 14, 2008, pages 3154 - 3163, XP002727099 7;
NAIR, ROSHNA V. ET AL: "A Synthetic Zipper Peptide Motif Orchestrated via Co-operative Interplay of Hydrogen Bonding, Aromatic Stacking, and Backbone Chirality", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY , 135(31), 11477-11480 CODEN: JACSAT; ISSN: 0002-7863, 2013, DOI: 10.1021/JA405455G 10.1021/JA405455G 7
|
| 56 |
Cited non-patent literature indicated by the applicant |
CTNP |
"GREEN 'S PROTECTIVE GROUPS IN ORGANIC SYNTHESIS", June 2013, WILEY-BLACKWELL 1;
"Remington's Pharmaceutical Sciences", 1985, pages: 1418 1;
ADAMCZYK, M.; FINO, J., R., ORG. PREP. PROCED. INT., vol. 28, 2009, pages 470 - 474 1;
CHARETTE ET AL., A. ORG. REACT., vol. 58, 2001, pages 1 1;
COELHO ET AL., SCIENCE, vol. 339, no. 6117, pages 307 - 310 1;
DAVIES, J. AM. CHEM. SOC., vol. 115, 1993, pages 9468 1;
KISHNER ET AL., J. RUSS. PHYS. CHEM. SOC., vol. 43, 1911, pages 1132 1;
LUDGER ET AL.: "Biosynthesis and Metabolism of Cyclopropane Rings in Natural Compounds", CHEM. REV., vol. 103, 2003, pages 1625 - 1648 1;
M. S. TICHENOR; D. B. KASTRINSKY; D. L. BOGER, J. AM. CHEM. SOC., vol. 126, 2004, pages 8396 1;
ORGANIC SYNTHESES, COLL., vol. 47, 1967, pages 98 1;
ORGANIC SYNTHESES, COLL., vol. 5, 1973, pages 929 1;
P. G. M. WUTS: "Greene's Protective Groups in Organic Synthesis", 2006, WILEY 1;
PAUL ET AL., J. AM. CHEM. SOC., vol. 128, no. 19, 2006, pages 6302 - 6303 1;
PEREZ, R., A.; FERNÁNDEZ-ALVAREZ, E.; NIETO, O.; JAVIER PIEDRAFITA, F., J. MED. CHEM., vol. 35, 1992, pages 4584 - 4588 1;
ZHANG ET AL., ORG. LETT., vol. 12, no. 17, 2010, pages 3942 - 3945 1
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Citing documents |
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Determine documents
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Sequence listings |
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Search file IPC |
ICP |
A61K 31/277
A61K 31/5375
A61P 31/04
C07C 233/83
C07C 255/03
C07C 255/57
C07C 311/21
C07D 207/34
C07D 241/28
C07D 277/56
C07D 295/14
C07D 307/56
C07D 317/08
C07D 333/38
C07F 9/09
|
