Bibliografische Daten

Dokument WO002011012553A1 (Seiten: 93)

Bibliografische Daten Dokument WO002011012553A1 (Seiten: 93)
INID Kriterium Feld Inhalt
54 Titel TI [EN] METHOD FOR PREDICTING THE LIKELIHOOD OF AN ONSET OF AN INFLAMMATION ASSOCIATED ORGAN FAILURE
[FR] PROCÉDÉ POUR PRÉDIRE LA PROBABILITÉ DE L’APPARITION D’UNE INSUFFISANCE D’ORGANE ASSOCIÉE À UNE INFLAMMATION
71/73 Anmelder/Inhaber PA BIOCRATES LIFE SCIENCES AG, AT ; DEIGNER HANS-PETER, AT ; ENOT DAVID, AT ; KELLER MATTHIAS, DE ; KOAL THERESE, AT ; KOHL MATTHIAS, DE
72 Erfinder IN DEIGNER HANS-PETER, AT ; ENOT DAVID, AT ; KELLER MATTHIAS, DE ; KOAL THERESE, AT ; KOHL MATTHIAS, DE
22/96 Anmeldedatum AD 23.07.2010
21 Anmeldenummer AN 2010060745
Anmeldeland AC EP
Veröffentlichungsdatum PUB 03.02.2011
33
31
32
Priorität PRC
PRN
PRD
EP
09167018
20090731
51 IPC-Hauptklasse ICM G01N 33/68 (2006.01)
51 IPC-Nebenklasse ICS
IPC-Zusatzklasse ICA
IPC-Indexklasse ICI
Gemeinsame Patentklassifikation CPC G01N 2800/26
G01N 33/6893
G16B 40/00
G16B 40/20
G16B 5/00
Y10T 436/173845
MCD-Hauptklasse MCM G01N 33/68 (2006.01)
MCD-Nebenklasse MCS G16B 40/20 (2019.01)
G16B 5/00 (2019.01)
MCD-Zusatzklasse MCA
57 Zusammenfassung AB [EN] The present invention relates to a reliable and statistically significant method for predicting the likelihood of an onset of an inflammation associated organ failure from a biological sample of a mammalian subject in vitro, by means of a subject's quantitative metabolomics profile comprising a plurality of endogenous metabolites, and comparing it with a quantitative reference metabolomics profile of a plurality of endogenous organ failure predictive target metabolites in order to predict whether the subject is likely or unlikely to develop an organ failure. Furthermore, the invention relates to the usefulness of endogenous organ failure predictive target metabolites in such a method.
[FR] La présente invention concerne un procédé fiable et statistiquement significatif pour prédire la probabilité de l'apparition d'une insuffisance d'organe associée à une inflammation à partir d'un échantillon biologique d'un sujet mammifère in vitro, au moyen d'un profil métabolomique quantitatif d'un sujet comprenant une pluralité de métabolites endogènes, et la comparaison de celui-ci avec un profil métabolomique de référence quantitatif d'une pluralité de métabolites cibles prédictifs d'une insuffisance d'organe endogène, afin de prédire si le sujet est susceptible ou non de développer une insuffisance d'organe. De plus, l'invention concerne l'utilité de métabolites endogènes cibles prédictifs d'une insuffisance d'organe dans un tel procédé.
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