54 |
Title |
TI |
[EN] TIME-RESOLVED NON-INVASIVE OPTOMETRIC DEVICE FOR DETECTING DIABETES |
71/73 |
Applicant/owner |
PA |
UNIV CALIFORNA, US
|
72 |
Inventor |
IN |
KATIKA KAMAL M, US
;
PILON LAURENT G, US
|
22/96 |
Application date |
AD |
Dec 13, 2006 |
21 |
Application number |
AN |
61042306 |
|
Country of application |
AC |
US |
|
Publication date |
PUB |
Jul 5, 2007 |
33 31 32 |
Priority data |
PRC PRN PRD |
US
2005021588
Jun 17, 2005
|
33 31 32 |
PRC PRN PRD |
US
58112304
Jun 17, 2004
|
51 |
IPC main class |
ICM |
A61B 5/00
(2006.01)
|
51 |
IPC secondary class |
ICS |
|
|
IPC additional class |
ICA |
|
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IPC index class |
ICI |
|
|
Cooperative patent classification |
CPC |
A61B 5/0059
A61B 5/0071
A61B 5/14532
A61B 5/1455
A61B 5/441
A61B 5/6816
A61B 5/6824
A61B 5/6825
A61B 5/6829
G01N 2021/6493
G01N 21/6408
G01N 21/6486
G01N 2800/042
G01N 33/582
G01N 33/6893
|
|
MCD main class |
MCM |
A61B 5/00
(2006.01)
|
|
MCD secondary class |
MCS |
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MCD additional class |
MCA |
|
57 |
Abstract |
AB |
[EN] A time-resolved fluorescence device is described for the detection and diagnosis of diabetes in a noninvasive manner. The device uses an ultra-short excitation pulse of light in the UV, infrared or visible range that comprises of a repetition of nanosecond pulses. The excitation pulse is directed incident onto a strategically selected area of the patient body such as the forearm, the feet, and the palm. This light interacts with the different layers of the skin. The absorbed light excites the AGEs in the skin, which in turn generate a fluorescence signal, which is collected by a detector. A processor is coupled to the detector to measure the transient fluorescence intensity decay of the skin in terms of lifetimes, and the contribution of individual fluorophores to the overall fluorescence signal. The nature and location of the fluorophores may be identified and a medical diagnostics may be performed. |
56 |
Cited documents identified in the search |
CT |
US000003087487A US000005222496A US000005448992A US000005492118A US000005572996A US000005676140A US000006319540B1 US000006384914B1 US000006584342B1 US000006675030B2 US000006567678B1 US000006721582B2 US000006728560B2 US000006806089B1 US020020082487A1 US020020158211A1 US020020193672A1 US020050148834A1
|
56 |
Cited documents indicated by the applicant |
CT |
|
56 |
Cited non-patent literature identified in the search |
CTNP |
|
56 |
Cited non-patent literature indicated by the applicant |
CTNP |
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Citing documents |
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Determine documents
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Sequence listings |
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Search file IPC |
ICP |
A61B 5/00
|