Bibliografische Daten

Dokument US000009926536B2 (Seiten: 55)

Bibliografische Daten Dokument US000009926536B2 (Seiten: 55)
INID Kriterium Feld Inhalt
54 Titel TI [EN] Glucose oxidase variants and methods of using the same
71/73 Anmelder/Inhaber PA ROCHE DIABETES CARE INC, US
72 Erfinder IN BOCOLA MARCO, DE ; DUEFEL HARTMUT, DE ; GUTIERREZ ERIK UWE ARANGO, DE ; HEINDL DIETER, DE ; MEIER THOMAS, DE ; MUNDHADA HEMANSHU, DK ; SCHWANEBERG ULRICH, BE ; TACKE MICHAEL, DE
22/96 Anmeldedatum AD 27.07.2015
21 Anmeldenummer AN 201514810070
Anmeldeland AC US
Veröffentlichungsdatum PUB 27.03.2018
33
31
32
Priorität PRC
PRN
PRD
EP
2014051602
28.01.2014
33
31
32
PRC
PRN
PRD
EP
13152935
28.01.2013
51 IPC-Hauptklasse ICM C12N 9/20 (2006.01)
51 IPC-Nebenklasse ICS C12N 9/04 (2006.01)
C12N 9/54 (2006.01)
C12Q 1/54 (2006.01)
IPC-Zusatzklasse ICA
IPC-Indexklasse ICI
Gemeinsame Patentklassifikation CPC C12N 9/0006
C12N 9/54
C12Q 1/54
C12Y 101/03004
G01N 2333/904
MCD-Hauptklasse MCM C12N 9/20 (2006.01)
MCD-Nebenklasse MCS C12N 9/04 (2006.01)
C12N 9/54 (2006.01)
C12Q 1/54 (2006.01)
MCD-Zusatzklasse MCA
57 Zusammenfassung AB [EN] Novel glucose oxidase (GOx) variants are disclosed that have the substitutions of T30V and I94V set forth in SEQ ID NO:1, and additionally at least one further amino acid substitution in the enzyme sequence in any of the positions S53; A137; A173; A332; F414 and V560. The GOx variants herein exhibit specificity for glucose and significantly reduced oxygen consumption rates and/or increased enzyme activity for electron mediators other than oxygen. Also provided are assay devices incorporating at least one of the GOx variants herein for improved blood glucose measurements.
56 Entgegengehaltene Patentdokumente/Zitate,
in Recherche ermittelt
CT US000005516671A
US000006376210B1
US000008999140B2
56 Entgegengehaltene Patentdokumente/Zitate,
vom Anmelder genannt
CT EP000000354441A2
EP000002415863A1
56 Entgegengehaltene Nichtpatentliteratur/Zitate,
in Recherche ermittelt
CTNP
56 Entgegengehaltene Nichtpatentliteratur/Zitate,
vom Anmelder genannt
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Prüfstoff-IPC ICP C12N 9/04
C12N 9/20
C12N 9/54
C12Q 1/54