56 |
Entgegengehaltene Nichtpatentliteratur/Zitate, vom Anmelder genannt |
CTNP |
Bokhari et al., "Regulation of Skin Microvasculature Angiogenesis, Cell Migration, and Permeability by a Specific Inhibitor of PKCalpha", J. Invest. Dermatol., 2006, 126 (2), 460-467. 1; Cabebe et al., "Sunitinib: A newly approved small-molecule inhibitor of angiogenesis", Drugs of Today, 2006, 42 (6), 387-398. 1; Davis et al., "Inhibitors of protein kinase C. 1. 2,3-Bisarylmaleimides", J. Med. Chem., 1992, 35, 177-184. 1; Davis et al., "Inhibitors of protein kinase C. 2. Substituted bisindolylmaleimides with improved potency and selectivity", J. Med. Chem., 1992, 35, 994-1001. 1; Faul et al., "A New One Step Synthesis of Maleimides by Condensation of Glyoxylate Esters with Acetamides", Tetrahedron Letters, 1999, 40, 1109-1112. 1; Faul et al., "A New, Efficient Method for the Synthesis of Bisindolylmaleimides", J. Org. Chem., 1998, 63, 6053-6058. 1; Faul et al., "Acyclic N-(azacycloalkyl)bisindolylmaleimides: Isozyme selective inhibitors of PKCbeta", Bioorg. Med. Chem. Lett., 2003, 13, 1857-1859. 1; Faul et al., "Cyclization strategies for the synthesis of macrocyclic bisindolylmaleimides", J. Org. Chem., 2001, 66, 2024-2033. 1; Hands et al., "A Convenient Method for the Preparation of 5-, 6- and 7-Azaindoles and Their Derivatives", Synthesis, 1996, 7, 877-882. 1; International Preliminary Report on Patentability for International Application No. PCT/EP2005/013126 (2006). 1; International Search Report for International Application No. PCT/EP2005/013126 (2006). 1; Mahadevan et al., "Synthesis of Pyrrolopyridines (Azaindoles)", J. Heterocycl. Chem., 1992, 29, 359-367. 1; O'Neill et al., "Design, synthesis and biological evaluation of novel 7-azaindolyl-heteroaryl-maleimides as potent and selective glycogen synthase kinase-3beta (GSK-3beta) inhibitors", Bioorg. Med. Chem., 2004, 12, 3167-3185. 1; Okauchi et al. , "A General Method for Acylation of Indoles at the 3-Position with Acyl Chlorides in the Presence of Dialkylaluminum Chloride", Organic Letters, 2000, 2 (10), 1485-1487. 1; Peifer et al., "A novel quantitative chick embryo assay as an angiogenesis model using digital image analysis", Anticancer Res., 2004, 24, 1545-1552. 1; Peifer et al., "Design, Synthesis, and Biological Evaluation of 3,4-Diarylmaleimides as Angiogenesis Inhibitors", J. Med. Chem., 2006, 49, 1271-1281. 1; Peifer et al., "Profile and Molecular Modeling of 3-(Indole-3-yl)-4-(3,4,5-trimethoxyphenyl)-1 H-pyrrole-2,5-dione (1) as a Highly Selective VEGF-R2/3 Inhibitor", J. Med. Chem., 2006, 49, 7549-7553. 1; Tanaka et al., "Synthesis of anilino-monoindolylmaleimides as potent and selective PKCbeta inhibitors", Bioorganic & Medicinal Chem. Lett., 2004,14, 5171-5174. 1; Tholander et al., "Syntheses of 6,12-Disubstituted 5,11-Dihydroindolo[3,2-b]carbazoles, Including 5,11-Dihydroindolo[3,2-b]carbazole-6,12-dicarbaldehyde, an Extremely Efficient Ligand for the TCDD (Ah) Receptor", Tetrahedron 1999, 55 (43), 12577-12594. 1; Xu et al., "Synthesis and cytotoxicity of indolopyrrolemaleimides", Chem. Pharm. Bull. (Tokyo), 2007, 55, 1302-1307. 1; Zhang et al., "3-(7-Azaindolyl)-4-arylmaleimides as potent, selective inhibitors of glycogen synthase Kinase-3", Bioorganic & Medicinal Chemistry Letters, 14(12), 3245-3250 (2004). 1; Zhang et al., "A General Method for the Preparation 4- and 6-Azaindoles", J. Org. Chem., 2002, 67, 2345-2347. 1; Zhang et al., "An Effective Procedure for the Acylation of Azaindoles at C-3", J. Org. Chem., 2002, 67, 6226-6227. 1; Zhang et al., "Novel indolylindazolylmaleimides as inhibitors of protein kinase C-beta: synthesis, biological activity, and cardiovascular safety", J. Med. Chem., 2005, 48, 1725-1728. 1
|