| 54 |
Title |
TI |
[DE] VERFAHREN ZUR HERSTELLUNG VON AMINEN AUS CARBONYLVERBINDUNGEN DURCH TRANSAMINASEREAKTION UNTER SALZFÄLLUNG
[EN] METHOD FOR PREPARING AMINES FROM CARBONYL COMPOUNDS BY TRANSAMINASE REACTION UNDER SALT PRECIPITATION
[FR] PROCÉDÉ DE PRÉPARATION D'AMINES À PARTIR DE COMPOSÉS CARBONYLES PAR RÉACTION DE TRANSAMINASE SOUS UNE PRÉCIPITATION DE SELS |
| 71/73 |
Applicant/owner |
PA |
ENZYMICALS AG, DE
;
UNIV ROSTOCK, DE
|
| 72 |
Inventor |
IN |
HÜLSEWEDE DENNIS, DE
;
MENYES ULF, DE
;
SÜSS PHILIPP, DE
;
TÄNZLER MARCO, DE
;
VON LANGERMANN JAN, DE
|
| 22/96 |
Application date |
AD |
Nov 17, 2017 |
| 21 |
Application number |
AN |
17202282 |
|
Country of application |
AC |
EP |
|
Publication date |
PUB |
May 22, 2019 |
33
31
32 |
Priority data |
PRC
PRN
PRD |
|
| 51 |
IPC main class |
ICM |
C12P 13/00
(2006.01)
|
| 51 |
IPC secondary class |
ICS |
|
|
IPC additional class |
ICA |
|
|
IPC index class |
ICI |
|
|
Cooperative patent classification |
CPC |
C07C 211/63
C07C 57/30
C12N 9/1096
C12P 13/00
C12P 13/001
C12P 13/005
C12P 7/40
|
|
MCD main class |
MCM |
C12P 13/00
(2006.01)
|
|
MCD secondary class |
MCS |
|
|
MCD additional class |
MCA |
|
| 57 |
Abstract |
AB |
[EN] The present invention relates to a method for preparing an amino salt compound comprising: i) providing a carbonyl compound; ii) reacting the carbonyl compound provided according to (i) in the presence of a transaminase with ii-a) at least one primary amine; and ii-b) at least one carboxylic acid; thereby obtaining a mixture comprising an at least partially crystallized amino salt compound comprising a cation and a carboxylate anion based on the at least one carboxylic acid added according to (ii-b). The invention also relates to an amino salt compound obtained or obtainable by the method and to the amino salt compound per se. Furthermore, the invention relates to a composition comprising a) an amine of general formula (Ila); and b) at least one carboxylic acid of general formula (III). |
| 56 |
Cited documents identified in the search |
CT |
WO002011026556A1
|
| 56 |
Cited documents indicated by the applicant |
CT |
|
| 56 |
Cited non-patent literature identified in the search |
CTNP |
BUQUE-TABOADA ET AL: "In situ product recovery (ISPR) by crystallization: basic principles, design, and potential applications in whole-cell biocatalysis", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, vol. 71, 2006, pages 1 - 12, XP019422047 0;
DATABASE UniParc [online] 14 April 2017 (2017-04-14), N.N.: "Mycobacterium bacteremicum", XP002780153, Database accession no. UPI0009F6A547 0;
HEINTZ ET AL: "Development of in situ product removal strategies in biocatalysis applying scaled-down unit operations", BIOTECHNOLOGY AND BIOENGINEERING, vol. 114, 12 October 2016 (2016-10-12), pages 600 - 609, XP002780154 0;
HÜLSEWEDE ET AL: "Development of an in situ-product crystallization (ISPC)-concept to shift the reaction equilibria of selected amine transaminase-catalyzed reactions", EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 10.1002/EJOC.201800323, March 2018 (2018-03-01), pages 1 - 5, XP002780145 0;
VON LANGERMANN: "Equilibrium displacement by in situ-product crystallisation (ISPC) in transaminase-catalysed reactions", CONFERENCE PRESENTATION, December 2018 (2018-12-01), pages 1 - 3, XP002780155, Retrieved from the Internet [retrieved on 20180417] 0
|
| 56 |
Cited non-patent literature indicated by the applicant |
CTNP |
|
|
Citing documents |
|
CN000111465699A
|
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Sequence listings |
|
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Search file IPC |
ICP |
C12P 13/00
|
