| 54 |
Title |
TI |
[DE] Strukturierbarer Polymer-Schichtverbund für Biomoleküle, Verfahren zu seiner Herstellung und Anwendung
[EN] Structured polymeric multilayered support for biomolecules, its production method and use
[FR] Support polymérique structuré pour des biomolécules, procédé de fabrication et utilisation |
| 71/73 |
Applicant/owner |
PA |
LEIBNIZ INST POLYMERFORSCHUNG, DE
|
| 72 |
Inventor |
IN |
MERTIG MICHAEL, DE
;
MILLARUELO BOIRA MARTHA, DE
;
OPITZ JOERG, DE
;
POMPE WOLFGANG, DE
;
SIECZKOWSKA BARBARA, DE
;
VOIGT JAN, DE
;
VOIT BRIGITTE, DE
|
| 22/96 |
Application date |
AD |
Nov 13, 2006 |
| 21 |
Application number |
AN |
06123899 |
|
Country of application |
AC |
EP |
|
Publication date |
PUB |
May 23, 2007 |
33
31
32 |
Priority data |
PRC
PRN
PRD |
DE
102005056016
20051117
|
| 51 |
IPC main class |
ICM |
B01J 19/00
(2006.01)
|
| 51 |
IPC secondary class |
ICS |
C12Q 1/68
(2006.01)
|
|
IPC additional class |
ICA |
|
|
IPC index class |
ICI |
|
|
Cooperative patent classification |
CPC |
B01J 19/0046
B01J 2219/00432
B01J 2219/00497
B01J 2219/00527
B01J 2219/00576
B01J 2219/0059
B01J 2219/00596
B01J 2219/00605
B01J 2219/00612
B01J 2219/00617
B01J 2219/00626
B01J 2219/0063
B01J 2219/00637
B01J 2219/00653
B01J 2219/00659
B01J 2219/00677
B01J 2219/00711
B01J 2219/00722
B01J 2219/00725
B82Y 30/00
|
|
MCD main class |
MCM |
B01J 19/00
(2006.01)
|
|
MCD secondary class |
MCS |
C12Q 1/68
(2006.01)
|
|
MCD additional class |
MCA |
|
| 57 |
Abstract |
AB |
[EN] The polymer composite layer for production of DNA networks on gold contacts, comprises a gold layer that is present on a substrate, structurable aminoterpolymer layer coated on the substrate and a chromium layer. The substrate is glass, metal, silicon or ceramic. The polymer contains aminoterpolymer layer and protective amino groups. The chromium layer is present between the substrate and the gold layer as electrode. Bio molecules in the aminoterpolymer are immobilized by means of chemical- and/or physical bond. The polymer composite layer for production of DNA networks on gold contacts, comprises a gold layer that is present on a substrate, structurable aminoterpolymer layer coated on the substrate and a chromium layer. The substrate is glass, metal, silicon or ceramic. The polymer contains aminoterpolymer layer and protective amino groups. The chromium layer is present between the substrate and the gold layer as electrode. Bio molecules in the aminoterpolymer are immobilized by means of chemical- and/or physical bond. The polymer layer contains adhesive group of thiol, disulfide or other active group containing sulfur, protective amino groups, primary- and aliphatic amino groups. The protective amino groups are present in the aminoterpolymer by means of ultraviolet radiation. The bio molecules are immobilized as DNA, proteins or enzymes. The bonding of the aminoterpolymers takes place at the gold surface by electrostatic interaction and/or a sulfur-bridge bond and by forming an amide-bond. The bio-molecules are end specifically immobilized on same or different areas of the amino groups. The structuring of the gold layer optionally agrees with the structuring of the areas of the protective amino groups. An independent claim is included for a procedure for the production of polymer composite layer. |
| 56 |
Cited documents identified in the search |
CT |
US000005847019A
WO001990010655A1
WO002002077287A1
WO002003029481A2
|
| 56 |
Cited documents indicated by the applicant |
CT |
|
| 56 |
Cited non-patent literature identified in the search |
CTNP |
VOIT B. ET AL: "Photo- and thermally labile polymers as templates and for surface patterning", PROCEEDING OF THE 8TH POLYMERS FOR ADVANCED TECHNOLOGIES INTERNATIONAL SYMPOSIUM, BUDAPEST, HUNGARY, 13 September 2005 (2005-09-13) - 16 September 2005 (2005-09-16), XP002425557, Retrieved from the Internet 0;
JÖRG OPITZ ET AL: "Site-specific binding and stretching of DNA molecules at UV-light-patterned aminoterpolymer films", 1 July 2004, NANOTECHNOLOGY, IOP, BRISTOL, GB, PAGE(S) 717-723, ISSN: 0957-4484, XP020067990 0
|
| 56 |
Cited non-patent literature indicated by the applicant |
CTNP |
|
|
Citing documents |
|
Determine documents
|
|
Sequence listings |
|
|
|
Search file IPC |
ICP |
C09D 177/00
C12Q 1/68
|
