| 54 |
Titel |
TI |
[DE] Ester des Hexahydro-8-hydroxy-2,6-methano-2H-chinolizin-3(4H)-ons und verwandte Verbindungen.
[EN] Esters of hexadydro-8-hydroxy-2,6-methano-2H-quinolizin-3(4H)-one and related compounds.
[FR] Esters de l'hexahydro-8-hydroxy-2,6-méthano-2H-quinolizin-3-(4H)-one et composés apparentés. |
| 71/73 |
Anmelder/Inhaber |
PA |
MERRELL DOW PHARMA, US
|
| 72 |
Erfinder |
IN |
GITTOS MAURICE WARD
|
| 22/96 |
Anmeldedatum |
AD |
02.11.1987 |
| 21 |
Anmeldenummer |
AN |
87116119 |
|
Anmeldeland |
AC |
EP |
|
Veröffentlichungsdatum |
PUB |
11.05.1988 |
33
31
32 |
Priorität |
PRC
PRN
PRD |
US
92661986
19861103
|
| 51 |
IPC-Hauptklasse |
ICM |
A61K 31/445
|
| 51 |
IPC-Nebenklasse |
ICS |
C07D 455/00
C07D 471/18
|
|
IPC-Zusatzklasse |
ICA |
|
|
IPC-Indexklasse |
ICI |
|
|
Gemeinsame Patentklassifikation |
CPC |
A61P 1/08
A61P 25/04
A61P 25/06
C07D 471/18
|
|
MCD-Hauptklasse |
MCM |
A61K 31/445
(2006.01)
|
|
MCD-Nebenklasse |
MCS |
A61K 31/435
(2006.01)
A61K 31/535
(2006.01)
A61P 1/08
(2006.01)
A61P 25/04
(2006.01)
A61P 25/06
(2006.01)
C07D 453/00
(2006.01)
C07D 471/18
(2006.01)
|
|
MCD-Zusatzklasse |
MCA |
|
| 57 |
Zusammenfassung |
AB |
[EN] The present invention is directed to a group of esters of hexahydro-8-hydroxy-2,6-methano-2H-quinolizin-3(4H)-one and related compounds. The compounds are prepared from the appropriate carboxylic acids and alcohols by standard procedures or, where steric factors are significant, a new process which makes use of heavy metal salts of super acids can be used. The compounds involved are useful in the treatment of migraine and similar disorders and in cytotoxic drug-induced vomiting. |
| 56 |
Entgegengehaltene Patentdokumente/Zitate,
in Recherche ermittelt |
CT |
|
| 56 |
Entgegengehaltene Patentdokumente/Zitate,
vom Anmelder genannt |
CT |
|
| 56 |
Entgegengehaltene Nichtpatentliteratur/Zitate,
in Recherche ermittelt |
CTNP |
Archiv Der Pharmazie, Vol. 309, 1976 W. SCHNEIDER et al.: "Beitrage zur Tropanchemie, 2. Mitt. Nortropan-3beta-Essigsaure, Tropachinuclidin und Dehydrotropachinuclidin" pages 447-457 * pages 448-452 * 0;
Archiv der Pharmazie, Vol. 308, 1975 W. SCHNEIDER et al.: "Beitrage zur Tropanchemie, 1. Mi-t. 3beta-Substituierte Tropan-Derivate" pages 365-375 * pages 366, 369, 370 * 0;
Helvetica Chimica Acta, Vol. 59, 1976 B. MAURER et al.: "Zur Kenntnis der Stickstoffhaltigen Inhaltsstoffe von Castoreum" pages 1169-1185 * pages 1177, 1179 * 0;
Journal of the Chemical Society Chemical Communication, 1976 P.G. SAMMES et al.: "Novel Heterocyclic Systems by Intramolecular Cycloadditions with Unactivated Olefins" pages 367-368 * page 368 * 0;
Tetrahedron Letters, Vol. 15, 1966 W. SCHNEIDER et al.: "9-Aza-Tricyclo (4.3.1.04,9) Decanon-(7) ("Tropachinuclidon")" pages 1583-1586 * pages 1584, 1586 * 0
|
| 56 |
Entgegengehaltene Nichtpatentliteratur/Zitate,
vom Anmelder genannt |
CTNP |
|
|
Zitierende Dokumente |
|
Dokumente ermitteln
|
|
Sequenzprotokoll |
|
|
|
Prüfstoff-IPC |
ICP |
C07D 455/02
C07D 471/18
|
