| 54 |
Titel |
TI |
[EN] NOVEL CYTOCHROME P-450 MONOOXYGENASES AND THEIR USING FOR OXIDATION OF ORGANIC COMPOUNDS
[XX] НОВЫЕ ЦИТОХРОМ Р450-МОНООКСИГЕНАЗЫ И ИХ ПРИМЕНЕНИЕ ДЛЯ ОКИСЛЕНИЯ ОРГАНИЧЕСКИХ СОЕДИНЕНИЙ |
| 71/73 |
Anmelder/Inhaber |
PA |
BASF AG, DE
|
| 72 |
Erfinder |
IN |
APPEL DANIEHL, DE
;
FISHER MARKUS, DE
;
KHAUEHR BERNKHARD, DE
;
LI KUING-SHAN, JP
;
LJUTTS-VAL SABINE, DE
;
PLJAJSS JUERGEN, DE
;
SHMID ROL F, DE
;
SHMITT JUTTA, DE
;
SHVANEBERG UL RIKH, DE
|
| 22/96 |
Anmeldedatum |
AD |
27.07.2000 |
| 21 |
Anmeldenummer |
AN |
2002105499 |
|
Anmeldeland |
AC |
RU |
|
Veröffentlichungsdatum |
PUB |
10.10.2006 |
33
31
32 |
Priorität |
PRC
PRN
PRD |
DE
19935115
27.07.1999
|
33
31
32 |
PRC
PRN
PRD |
DE
19955605
18.11.1999
|
| 51 |
IPC-Hauptklasse |
ICM |
C12N 15/53
(2006.01)
|
| 51 |
IPC-Nebenklasse |
ICS |
C12N 9/02
(2006.01)
C12P 17/10
(2006.01)
C12P 17/16
(2006.01)
C12P 7/04
(2006.01)
C12P 7/22
(2006.01)
|
|
IPC-Zusatzklasse |
ICA |
|
|
IPC-Indexklasse |
ICI |
|
|
Gemeinsame Patentklassifikation |
CPC |
|
|
MCD-Hauptklasse |
MCM |
C12N 15/53
(2006.01)
|
|
MCD-Nebenklasse |
MCS |
C12N 9/02
(2006.01)
C12P 17/10
(2006.01)
C12P 17/16
(2006.01)
C12P 7/04
(2006.01)
C12P 7/22
(2006.01)
|
|
MCD-Zusatzklasse |
MCA |
|
| 57 |
Zusammenfassung |
AB |
[EN] FIELD: biotechnology, biochemistry, enzymes, microbiology. ^ SUBSTANCE: invention proposes a method for microbiological oxidation of N-, O- or S-heterocyclic mono- or multinuclear aromatic compounds. The method involves culturing the recombinant microorganism that expresses cytochrome P-450-dependent monooxygenase BM-3 from Bacillus megaterium with amino acid sequence represented in SEQ ID NO:2 that comprises at least one functional mutation in region 86-88 and, if necessary, at least one functional mutation in one of regions 73-82, 172-224, 39-43, 48-52, 67-170, 300-335 and 352-356. The prepared oxidation product is isolated from medium, Invention provides carrying out oxidation of organic compounds with enhanced degree of effectiveness. ^ EFFECT: enhanced effectiveness of enzymes. ^ 17 cl, 1 tbl, 7 ex |
| 56 |
Entgegengehaltene Patentdokumente/Zitate,
in Recherche ermittelt |
CT |
|
| 56 |
Entgegengehaltene Patentdokumente/Zitate,
vom Anmelder genannt |
CT |
|
| 56 |
Entgegengehaltene Nichtpatentliteratur/Zitate,
in Recherche ermittelt |
CTNP |
|
| 56 |
Entgegengehaltene Nichtpatentliteratur/Zitate,
vom Anmelder genannt |
CTNP |
|
|
Zitierende Dokumente |
|
Dokumente ermitteln
|
|
Sequenzprotokoll |
|
|
|
Prüfstoff-IPC |
ICP |
|
